Variants of psychiatric disorders in patients with systemic lupus erythematosus

Variants of psychiatric disorders in patients with systemic lupus erythematosus

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Objective.To analyze prevalence and structure Bangers of psychiatric disorders in pts with systemic lupus erythematosus (SLE) examining in the Institute of rheumatology of RAMS.Material and methods.115 pts with SLE with median age 34 [24; 45] years and median disease duration 8 [4; 17] years were included.SLE activity was assessed with SLEDAI.

Psychiatric disorders were diagnosed by a psychiatrist according to ICD-10 using some psychiatric and psychological scales.Results.Psychiatric disorders were revealed in 76 from 115 (66%) pts.Anxiety-depressive spectrum disorders prevailed (83%): depressive episode (40%), adjustment disorders (24%), generalized anxiety disorder (10%), dysthymia (9%).Severe cognitive dysfunction was revealed in 7% of pts.

Pts with and without psychiatric disorders did not significantly differ in age, sex, duration and activity of the Model Paint disease, duration of treatment and cumulative dose of prednisolone and cytotoxic drugs.Conclusion.Psychiatric disorders are frequent in pts with SLE (66%).Anxiety-depressive disorders prevail among them (83%).Relationship between SLE and psychiatric disorders requires further examination.